Exenatide is a medication that is sold under the brand name bydureon and is prescribed to people with type 2 diabetes in order to improve the blood sugar levels.
As of now, Bydureon comes in two forms – a pen injector and a syringe – in the market and both are given underneath the skin.
bydureon consists of a drug called extended-release exenatide, which belongs to the ‘GLP-1 or glucagon-like peptide-1 agonists’ class of drugs.
Don’t Confuse bydureon with bydureon BCise
Another form of bydureon is bydureon BCise, which contains the same extended-release exenatide drug. Besides, both these drugs function in a similar manner and have similar effects on your body.
However, the major difference between these two drugs is that you need a special injector called autoinjector to take this medication underneath the skin. You simply need to do push the autoinjector against your skin and the medication will be automatically injected into your body.
The plus point here is that you need to take fewer steps using the autoinjector as compared to the pen injector or syringe. This makes using autoinjector a lot easier.
bydureon Usage Instructions
Here, you must keep in mind the instructions given by your doctor on how to use Byrideon.
When you are taking Bydureon, there are high chances that you will be using a pen or a syringe. The instructions that you need to follow in both cases are a bit different from one another. So, you need to take different steps for different forms.
In order to avoid any mistake when taking Bydureon, make sure you watch the video by the manufacturer.
Irrespective of which form of the drug (Bydureon) you are taking, you must be injecting in into your stomach or thigh or probably in the back of one of your arms. While you can take the injection into the same are, you must change the spot to avoid the chances of allergy or reaction.
While you can inject bydureon into your body at any time of the day, even with or without food, it is recommended to take your dose at the same time on the same day every week. In case you need to change the injection day, you can change it as per your convenience, but make sure there is a gap of at least 3 days between the two consecutive doses.
Doctors usually recommend taking your dose at the same time whether or not you change the day. You can always ask your doctor if you want to change the time.
Based on the approval of the Food and Drug Administration (FDA), there are certain conditions wherein Bydureon is prescribed. However, this drug is often used off-label for the treatment of certain other conditions.
Note: When a drug is used to treat a condition that is not approved by the FDA, it’s called off-label use of the drug.
- FDA-approved Uses of Bydureon
As per the FDA, bydureon can be used for the treatment of only one condition.
Bydureon for Type 2 Diabetes
Bydureon is an FDA-approved drug to improve the blood sugar levels in adults who have the condition of type 2 diabetes.
Based on multiple studies, bydureon was found to reduce hemoglobin A1c (HbA1c) by up to 0.8 to 1.6 percent after a treatment of 24 to 48 weeks.
- Off-label Uses of Bydureon
As of now, bydureon is only approved to be used as a drug to improve blood sugar levels in adult individuals with type 2 diabetes.
For Weight Loss
One common side effect of bydureon is suppressed appetite. In fact, many people who have been taking this drug observed suppressed appetite and weight loss eventually.
Based on some studies, people taking bydureon have lost up to 4.4 pounds over a period of 26 weeks of usage.
Important: Since bydureon is not an FDA approved weight loss supplement, it’s not recommended to anyone for this purpose. Take bydureon as and when prescribed by your doctor.
How Bydureon Works?
bydureon is approved by the FDA as a drug to improve blood sugar levels in people with type 2 diabetes.
Effects of Insulin on Blood Sugar
When you eat food, there is a hormone called Insulin released in your body. The primary function of Insulin is to help transport glucose released as a result of food breakdown from your bloodstream to the cells in your body. These cells then transform the glucose into energy.
In simple words, people with type 2 diabetes have a permanent condition of Insulin Resistance. This also means that their body fails to respond to Insulin the way it normally should. Insulin production in the body of these people stops eventually, and this condition leads to problems.
One of such problems is that your body cells don’t get glucose to produce the energy required to function properly. This eventually leads to too much glucose in your bloodstream, which is the condition of high blood sugar or hyperglycemia.
This state of high blood sugar can damage multiple organs in your body, including eyes, kidneys, nerves, and heart.
What does Bydureon do?
As already mentioned above, Bydureon belongs to the GLP-1 Agonists class of drug. The primary function of this drug is to increase the amount of insulin your body naturally produces when there is a high amount of glucose in your bloodstream (typically after eating).
The increased Insulin levels in your body carry more glucose to your body cells, leading to reduced glucose in your blood.
Bydureon also helps block the glucagon hormone production by your liver, thereby decreasing the glucose levels in your blood. Another function of this drug is to ensure that the food comes slowly out of your stomach, which ultimately helps control the release of glucose in your blood and thus maintains blood sugar levels.
While Bydureon starts working right after you inject it into your body, it builds up its effects over a period of several weeks.